作者
Joao PG Santos, Kadri Pajo, Daniel Trpevski, Andrey Stepaniuk, Olivia Eriksson, Anu G Nair, Daniel Keller, Jeanette Hellgren Kotaleski, Andrei Kramer
发表日期
2021
期刊
Neuroinformatics
页码范围
1-19
简介
Neuroscience incorporates knowledge from a range of scales, from single molecules to brain wide neural networks. Modeling is a valuable tool in understanding processes at a single scale or the interactions between two adjacent scales and researchers use a variety of different software tools in the model building and analysis process. Here we focus on the scale of biochemical pathways, which is one of the main objects of study in systems biology. While systems biology is among the more standardized fields, conversion between different model formats and interoperability between various tools is still somewhat problematic. To offer our take on tackling these shortcomings and by keeping in mind the FAIR (findability, accessibility, interoperability, reusability) data principles, we have developed a workflow for building and analyzing biochemical pathway models, using pre-existing tools that could be utilized …
学术搜索中的文章
JPG Santos, K Pajo, D Trpevski, A Stepaniuk… - Neuroinformatics, 2022