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Analog least mean square (ALMS) loop is a promising mechanism to suppress self-interference (SI) in an in-band full-duplex (IBFD) system. In this letter, a general solution for the weighting error function is derived to investigate the performance of the ALMS loop employed in any IBFD system. The solution is then applied to IBFD systems with single carrier and multi-carrier signaling. Due to the cyclostationary property of the transmitted signal, the weighting error function in the multi-carrier system varies more significantly than in the single carrier. Therefore, if the ALMS loop can perfectly mimic the SI channel, SI in the single carrier system can be suppressed to a much smaller level than that in the multi-carrier counterpart.