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QRS detection performance can depend on the type of noise present in each lead involved in the overall processing. A common approach to QRS detection is based on a QRS enhanced signal obtained from the derivatives of the pre-filtered leads. However, the signal pre-filtering cannot be able to perform a complete noise rejection and the use of derivatives can enhance the noise as well. In many cases the noise occurs only on one lead and the addition of a noisy lead to the QRS enhanced signal decreases the overall detection performances of the QRS detector. For this reason the noise estimation on each channel, providing information for the channel inclusion or rejection in building the QRS enhanced signal, can improve the overall performances of the QRS detector. The results have been evaluated on the 48 records of the MIT-BIH Arrhythmia Database where each ECG record is composed by 2 leads …