作者
Rafea Shaaban, Mahmoud Zureik, David Soussan, Catherine Neukirch, Joachim Heinrich, Jordi Sunyer, Matthias Wjst, Isa Cerveri, Isabelle Pin, Jean Bousquet, Deborah Jarvis, Peter G Burney, Françoise Neukirch, Bénédicte Leynaert
发表日期
2008/9/20
期刊
The Lancet
卷号
372
期号
9643
页码范围
1049-1057
出版商
Elsevier
简介
Background
A close relation between asthma and allergic rhinitis has been reported by several epidemiological and clinical studies. However, the nature of this relation remains unclear. We used the follow-up data from the European Community Respiratory Health Survey to investigate the onset of asthma in patients with allergic and non-allergic rhinitis during an 8·8-year period.
Methods
We did a longitudinal population-based study, which included 29 centres (14 countries) mostly in western Europe. Frequency of asthma was studied in 6461 participants, aged 20–44 years, without asthma at baseline. Incident asthma was defined as reporting ever having had asthma confirmed by a physician between the two surveys. Atopy was defined as a positive skin-prick test to mites, cat, Alternaria, Cladosporium, grass, birch, Parietaria, olive, or ragweed. Participants were classified into four groups at baseline: controls (no …
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