作者
Zhicheng Xu, Weiwen Wang, Tao Yang, Ling Li, Xizheng Ma, Jing Chen, Jieyu Wang, Yan Huang, Joshua Gould, Huifang Lu, Wensi Du, Sunil Kumar Sahu, Fan Yang, Zhiyong Li, Qingjiang Hu, Cong Hua, Shoujie Hu, Yiqun Liu, Jia Cai, Lijin You, Yong Zhang, YuXiang Li, Wenjun Zeng, Ao Chen, Bo Wang, Longqi Liu, Fengzhen Chen, Kailong Ma, Xun Xu, Xiaofeng Wei
发表日期
2024/1/5
期刊
Nucleic acids research
卷号
52
期号
D1
页码范围
D1053-D1061
出版商
Oxford University Press
简介
Recent technological developments in spatial transcriptomics allow researchers to measure gene expression of cells and their spatial locations at the single-cell level, generating detailed biological insight into biological processes. A comprehensive database could facilitate the sharing of spatial transcriptomic data and streamline the data acquisition process for researchers. Here, we present the Spatial TranscriptOmics DataBase (STOmicsDB), a database that serves as a one-stop hub for spatial transcriptomics. STOmicsDB integrates 218 manually curated datasets representing 17 species. We annotated cell types, identified spatial regions and genes, and performed cell-cell interaction analysis for these datasets. STOmicsDB features a user-friendly interface for the rapid visualization of millions of cells. To further facilitate the reusability and interoperability of spatial transcriptomic data, we developed …
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Z Xu, W Wang, T Yang, L Li, X Ma, J Chen, J Wang… - Nucleic acids research, 2024