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Advances in bottom-up nanofabrication have led to the use of various nanomaterials with superior physical properties as building blocks for the assembly of devices with complex configurations.[1–11] Peptide nanotubes are useful nanomaterial building blocks that have been used to construct a variety of device geometries, as their self-assembly is robust, and locations for their immobilization on substrates can be targeted by biomolecular recognition.[12, 13] However, one of the unexplored areas in devices based on peptide nanotubes is the lab-on-chip sensor. Herein, we examine the feasibility of assembling peptide-nanotube sensors with a simple chip geometry (Figure 1) for the electrical detection of viruses with an extremely low detection limit. Pathogen sensors based on peptide nanotubes have a few distinctive features. First, peptide nanotubes can incorporate any antibodies for viruses without destroying …