作者
Chuanhao Jiang, Yali Wang, Min Hu, Lingjun Wen, Chuan Wen, Yang Wang, Weihong Zhu, Shi Tai, Zhongbiao Jiang, Kui Xiao, Nuno Rodrigues Faria, Erik De Clercq, Junmei Xu, Guangdi Li
发表日期
2020
期刊
Clinical & translational immunology
卷号
9
期号
9
页码范围
e1182
简介
Objectives
Asymptomatic and symptomatic patients may transmit severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but their clinical features and immune responses remain largely unclear. We aimed to characterise the clinical features and immune responses of asymptomatic and symptomatic patients infected with SARS‐CoV‐2.
Methods
We collected clinical, laboratory and epidemiological records of patients hospitalised in a coronavirus field hospital in Wuhan. We performed qualitative detection of anti‐SARS‐CoV‐2 immunoglobulin M (IgM) and immunoglobulin G (IgG) using archived blood samples.
Results
Of 214 patients with SARS‐CoV‐2, 26 (12%) were asymptomatic at hospital admission and during hospitalisation. Most asymptomatic patients were ≤ 60 years (96%) and females (65%) and had few comorbidities (< 16%). Serum levels of white and red blood cells were higher in …
学术搜索中的文章
C Jiang, Y Wang, M Hu, L Wen, C Wen, Y Wang, W Zhu… - Clinical & translational immunology, 2020