作者
Emanuele Di Angelantonio, Stephen Kaptoge, David Wormser, Peter Willeit, Adam S Butterworth, Narinder Bansal, Linda M O’Keeffe, Pei Gao, Angela M Wood, Stephen Burgess, Daniel F Freitag, Lisa Pennells, Sanne A Peters, Carole L Hart, Lise Lund Håheim, Richard F Gillum, Børge G Nordestgaard, Bruce M Psaty, Bu B Yeap, Matthew W Knuiman, Paul J Nietert, Jussi Kauhanen, Jukka T Salonen, Lewis H Kuller, Leon A Simons, Yvonne T Van Der Schouw, Elizabeth Barrett-Connor, Randi Selmer, Carlos J Crespo, Beatriz Rodriguez, WM Monique Verschuren, Veikko Salomaa, Kurt Svärdsudd, Pim Van Der Harst, Cecilia Björkelund, Lars Wilhelmsen, Robert B Wallace, Hermann Brenner, Philippe Amouyel, Elizabeth LM Barr, Hiroyasu Iso, Altan Onat, Maurizio Trevisan, Ralph B D'agostino, Cyrus Cooper, Maryam Kavousi, Lennart Welin, Ronan Roussel, Frank B Hu, Shinichi Sato, Karina W Davidson, Barbara V Howard, Maarten JG Leening, Annika Rosengren, Marcus Dörr, Dorly JH Deeg, Stefan Kiechl, Coen DA Stehouwer, Aulikki Nissinen, Simona Giampaoli, Chiara Donfrancesco, Daan Kromhout, Jackie F Price, Annette Peters, Tom W Meade, Edoardo Casiglia, Debbie A Lawlor, John Gallacher, Dorothea Nagel, Oscar H Franco, Gerd Assmann, Gilles R Dagenais, J Wouter Jukema, Johan Sundström, Mark Woodward, Eric J Brunner, Kay-Tee Khaw, Nicholas J Wareham, Eric A Whitsel, Inger Njølstad, Bo Hedblad, Sylvia Wassertheil-Smoller, Gunnar Engström, Wayne D Rosamond, Elizabeth Selvin, Naveed Sattar, Simon G Thompson, John Danesh, Emerging Risk Factors Collaboration
发表日期
2015/7/7
期刊
Jama
卷号
314
期号
1
页码范围
52-60
出版商
American Medical Association
简介
Importance
The prevalence of cardiometabolic multimorbidity is increasing.
Objective
To estimate reductions in life expectancy associated with cardiometabolic multimorbidity.
Design, Setting, and Participants
Age- and sex-adjusted mortality rates and hazard ratios (HRs) were calculated using individual participant data from the Emerging Risk Factors Collaboration (689 300 participants; 91 cohorts; years of baseline surveys: 1960-2007; latest mortality follow-up: April 2013; 128 843 deaths). The HRs from the Emerging Risk Factors Collaboration were compared with those from the UK Biobank (499 808 participants; years of baseline surveys: 2006-2010; latest mortality follow-up: November 2013; 7995 deaths). Cumulative survival was estimated by applying calculated age-specific HRs for mortality to contemporary US age-specific death rates.
Exposures
A history of 2 or more of the following: diabetes mellitus …
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E Di Angelantonio, S Kaptoge, D Wormser, P Willeit… - Jama, 2015