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Due to the distributed nature of Denial-of-Service attacks, it is tremendously challenging to identify such malicious behavior using traditional intrusion detection systems in Wireless Sensor Networks (WSNs). In the current paper, a bio-inspired method is introduced, namely the cooperative-based fuzzy artificial immune system (Co-FAIS). It is a modular-based defense strategy derived from the danger theory of the human immune system. The agents synchronize and work with one another to calculate the abnormality of sensor behavior in terms of context antigen value (CAV) or attackers and update the fuzzy activation threshold for security response. In such a multi-node circumstance, the sniffer module adapts to the sink node to audit data by analyzing the packet components and sending the log file to the next layer. The fuzzy misuse detector module (FMDM) integrates with a danger detector module to identify the …