作者
Michael Soussan, Noémie Abisror, Sébastien Abad, Hilario Nunes, Benjamin Terrier, Gabriel Pop, Veronique Eder, Dominique Valeyre, Rebecca Sberro-Soussan, Loic Guillevin, Robin Dhote, Olivier Fain, Arsène Mekinian
发表日期
2014/2/1
来源
Autoimmunity reviews
卷号
13
期号
2
页码范围
125-131
出版商
Elsevier
简介
Objectives
We aimed to assess the clinical value of FDG-PET/CT in patients with ANCA-associated vasculitis.
Materials and methods
We retrospectively included 16 patients with ANCA-associated vasculitis who underwent 21 FDG-PET/CT between 2009 and 2013, in 2 university hospitals from the Paris suburb area. All FDG-PET/CTs were retrospectively analyzed and compared to clinical, biological and conventional imaging data at baseline and during the follow-up.
Results
ANCA-associated vasculitis was granulomatosis with polyangiitis (GPA, n = 10), microscopic polyangiitis (MPA, n = 4), and eosinophilic GPA (EGPA, n = 2). PET was performed at initial presentation in 14 cases and during the follow-up in 7 cases. At baseline, PET was positive in 100% of GPA patients (8/8) and in 50% (3/6) of patients with other ANCA-vasculitis (p = 0.05). FDG uptake tended to be higher in patients with GPA in comparison to …
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