作者
Uria Shani, Niv Ben-Shabat, Roula Qassem, Adi Lahat, Mahmud Omar, Einat Savin, Arad Dotan, Yonatan Shneor Patt, Lior Fisher, Galia Zacay, Howard Amital, Abdulla Watad, Kassem Sharif
发表日期
2024/1
期刊
Therapeutic Advances in Gastroenterology
卷号
17
页码范围
17562848241227037
出版商
SAGE Publications
简介
Background
The skin–gut axis, characterized by bidirectional communication between the skin and gut, plays a crucial role in the pathogenesis of psoriasis and inflammatory bowel diseases (IBD).
Objectives
We aimed to explore the association between psoriasis and IBD and identify predictors associated with IBD development among patients with psoriasis.
Design
Retrospective cohort study.
Methods
A retrospective study which utilized an electronic database from the Meuhedet Health Maintenance Organization (MHMO) in Israel. Psoriasis was categorized as severe if any systemic agent or phototherapy was administered. Univariate and multivariate logistic regressions were used to identify specific predictors for IBD, with adjustments made for potential confounders. The study received approval from the Ethical Committee of the MHMO.
Results
In total, 61,003 adult patients who were diagnosed with psoriasis …
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U Shani, N Ben-Shabat, R Qassem, A Lahat, M Omar… - Therapeutic Advances in Gastroenterology, 2024