作者
Rodrigo A Cornejo, Juan C Díaz, Eduardo A Tobar, Alejandro R Bruhn, Cristobal A Ramos, Roberto A González, Claudia A Repetto, Carlos M Romero, Luis R Gálvez, Osvaldo Llanos, Daniel H Arellano, Wilson R Neira, Gonzalo A Díaz, Aníbal J Zamorano, Gonzalo L Pereira
发表日期
2013/8/15
期刊
American journal of respiratory and critical care medicine
卷号
188
期号
4
页码范围
440-448
出版商
American Thoracic Society
简介
Rationale: Positive end-expiratory pressure (PEEP) and prone positioning may induce lung recruitment and affect alveolar dynamics in acute respiratory distress syndrome (ARDS). Whether there is interdependence between the effects of PEEP and prone positioning on these variables is unknown.
Objectives: To determine the effects of high PEEP and prone positioning on lung recruitment, cyclic recruitment/derecruitment, and tidal hyperinflation and how these effects are influenced by lung recruitability.
Methods: Mechanically ventilated patients (Vt 6 ml/kg ideal body weight) underwent whole-lung computed tomography (CT) during breath-holding sessions at airway pressures of 5, 15, and 45 cm H2O and Cine-CTs on a fixed thoracic transverse slice at PEEP 5 and 15 cm H2O. CT images were repeated in supine and prone positioning. A recruitment maneuver at 45 cm H2O was performed before each PEEP …
学术搜索中的文章
Effects of prone positioning on lung protection in patients with acute respiratory distress syndrome
RA Cornejo, JC Díaz, EA Tobar, AR Bruhn, CA Ramos… - American journal of respiratory and critical care …, 2013