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Introduction: Chronic Kidney Disease (CKD) refers to a group of heterogeneous disorders that results in gradual loss of structure and function of the kidneys.

Aim: To evaluate the role of glycated haemoglobin (HBA1c) due to type II diabetes mellitus by correlating glycated haemoglobin with estimated Glomerular Filtration Rate (GFR) and serum creatinine parameters.

Materials and Methods: This study was conducted over a period of one year during which 60 patients with CKD were enrolled for the study. Sixty age and sex matched controls were also enrolled. The diagnosis of CKD was done based on estimated Glomerular Filtration Rate (eGFR) calculation after obtaining history/clinico-pathological information. Blood samples were analysed for the following parameters: fasting blood sugar, HBA1c, blood urea, serum creatinine, serum albumin and electrolytes. The eGFR was calculated by using Modification of Diet in Renal Disease equation. Statistical analysis was done by using SPSS software.

Results: On comparison, the values of fasting blood sugar, HBA1c, blood urea, serum creatinine and serum potassium levels were significantly higher in CKD cases than in controls (p< 0.001). The values of haemoglobin and serum albumin were found to be significantly lower in the cases than the control group (p< 0.001). Among the CKD cases, correlation studies were done. HBA1c values negatively correlated with eGFR and positively correlated with serum creatinine values. The CKD cases were subdivided based on their stage (stage 3, 4 and 5) and compared with each other. A statistically significant difference (p< 0.001) between median values of …