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There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method com prises orally administering to the subject an effective pain relieving amount of a composition comprising celecoXib formulated in such a Way as to provide, When tested in fasting humans in accordance With standard pharmacoki netic practice, a blood plasma concentration pro? le of cele coXib in Which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral adminis tration.