作者
Jie-Bin Lew, Kate T Simms, Megan A Smith, Michaela Hall, Yoon-Jung Kang, Xiang Ming Xu, Michael Caruana, Louiza Sofia Velentzis, Tracey Bessell, Marion Saville, Ian Hammond, Karen Canfell
发表日期
2017/2/1
期刊
The Lancet Public Health
卷号
2
期号
2
页码范围
e96-e107
出版商
Elsevier
简介
Background
Australia's National Cervical Screening Program currently recommends cytological screening every 2 years for women aged 18–69 years. Human papillomavirus (HPV) vaccination was implemented in 2007 with high population coverage, and falls in high-grade lesions in young women have been reported extensively. This decline prompted a major review of the National Cervical Screening Program and new clinical management guidelines, for which we undertook this analysis.
Methods
We did effectiveness modelling and an economic assessment of potential new screening strategies, using a model of HPV transmission, vaccination, natural history, and cervical screening. First, we evaluated 132 screening strategies, including those based on cytology and primary HPV testing. Second, after a recommendation was made to adopt primary HPV screening with partial genotyping and direct referral to …
学术搜索中的文章
JB Lew, KT Simms, MA Smith, M Hall, YJ Kang, XM Xu… - The Lancet Public Health, 2017