作者
Rochelle Buffenstein, Vincent Amoroso, Blazej Andziak, Stanislav Avdieiev, Jorge Azpurua, Alison J Barker, Nigel C Bennett, Miguel A Brieño‐Enríquez, Gary N Bronner, Clive Coen, Martha A Delaney, Christine M Dengler‐Crish, Yael H Edrey, Chris G Faulkes, Daniel Frankel, Gerard Friedlander, Patrick A Gibney, Vera Gorbunova, Christopher Hine, Melissa M Holmes, Jennifer UM Jarvis, Yoshimi Kawamura, Nobuyuki Kutsukake, Cynthia Kenyon, Walid T Khaled, Takefumi Kikusui, Joseph Kissil, Samantha Lagestee, John Larson, Amanda Lauer, Leonid A Lavrenchenko, Angela Lee, Jonathan B Levitt, Gary R Lewin, Kaitlyn N Lewis Hardell, TzuHua D Lin, Matthew J Mason, Dan McCloskey, Mary McMahon, Kyoko Miura, Kazutaka Mogi, Vikram Narayan, Timothy P O'Connor, Kazuo Okanoya, M Justin O'Riain, Thomas J Park, Ned J Place, Katie Podshivalova, Matthew E Pamenter, Sonja J Pyott, Jane Reznick, J Graham Ruby, Adam B Salmon, Joseph Santos‐Sacchi, Diana K Sarko, Andrei Seluanov, Alyssa Shepard, Megan Smith, Kenneth B Storey, Xiao Tian, Emily N Vice, Mélanie Viltard, Akiyuki Watarai, Ewa Wywial, Masanori Yamakawa, Elena D Zemlemerova, Michael Zions, Ewan St John Smith
发表日期
2022/2
来源
Biological Reviews
卷号
97
期号
1
页码范围
115-140
出版商
Blackwell Publishing Ltd
简介
The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but also because of unusual protective features (e.g. its tolerance of variable oxygen availability), which may be pertinent to several human disease states, including ischemia/reperfusion injury and neurodegeneration. A recent article entitled ‘Surprisingly long survival of premature conclusions about naked mole‐rat biology’ described 28 ‘myths’ which, those authors claimed, are a ‘perpetuation of beautiful, but falsified, hypotheses’ and impede our understanding of this enigmatic mammal. Here, we re‐examine each of these ‘myths’ based on evidence published in the scientific literature. Following Braude et al., we argue that these ‘myths’ fall into four main categories: (i) ‘myths’ that would be better described as …
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