作者
Amir Y Shaikh, Nada Esa, William Martin-Doyle, Menhel Kinno, Iryna Nieto, Kevin C Floyd, Clifford Browning, Cynthia Ennis, J Kevin Donahue, Lawrence S Rosenthal, David D McManus
发表日期
2015/12/1
期刊
Critical pathways in cardiology
卷号
14
期号
4
页码范围
157-165
出版商
LWW
简介
Methods:
One hundred sixty-one patients with paroxysmal or persistent AF underwent an index PVI procedure between 2010 and 2013; 77 patients (48%) had late AF recurrence after PVI (> 3 months post-PVI) over the 6-month follow-up period.
Results:
A BNP greater than or equal to 100 pg/dL (P= 0.01) and AF recurrence within 3 months after PVI (P< 0.001) were associated with late AF recurrence in multivariate analyses. Addition of BNP to existing clinical risk scores significantly improved the areas under the curve for each score, with an integrated discrimination improvement of 0.08 (P= 0.001) and a net reclassification improvement of 60%(P= 0.001) for all risk scores.
Conclusions:
Circulating BNP levels are independently associated with late AF recurrence after PVI. Inclusion of BNP significantly improves the discriminative ability of CHADS2, CHA2DS2-VASc, R2CHADS2, and the HATCH score in predicting …
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AY Shaikh, N Esa, W Martin-Doyle, M Kinno, I Nieto… - Critical pathways in cardiology, 2015