作者
Jamie L Hanson, Moo K Chung, Brian B Avants, Elizabeth A Shirtcliff, James C Gee, Richard J Davidson, Seth D Pollak
发表日期
2010/6/2
期刊
Journal of neuroscience
卷号
30
期号
22
页码范围
7466-7472
出版商
Society for Neuroscience
简介
Individuals who experience early adversity, such as child maltreatment, are at heightened risk for a broad array of social and health difficulties. However, little is known about how this behavioral risk is instantiated in the brain. Here we examine a neurobiological contribution to individual differences in human behavior using methodology appropriate for use with pediatric populations paired with an in-depth measure of social behavior. We show that alterations in the orbitofrontal cortex among individuals who experienced physical abuse are related to social difficulties. These data suggest a biological mechanism linking early social learning to later behavioral outcomes.
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JL Hanson, MK Chung, BB Avants, EA Shirtcliff, JC Gee… - Journal of neuroscience, 2010