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The 27th International Conference on Pharmacoepidemiology and Therapeutic Risk Management was held in Chicago, IL, USA on 14–17 August 2011. This report focuses on presentations where clinically relevant drug safety alerts were announced or confirmed. The abstract number in each summary refers to the full abstract, which is published in Pharmacoepidemiology and Drug Safety (2011) 20 (Suppl 1): S1–S364.

Analgesic drugs Danish databases were analysed for prescription of chronic paracetamol use during pregnancy (1996–2008) to see if it had led to an increased risk of asthma in offspring (Ane Brigitte Andersen et al. Aarhus University, Denmark; Abstract 166). A total of 976 out of 197,071 (0.5%) children born during this time period had been prenatally exposed to maternal paracetamol use. Increased absolute risk of asthma in exposed versus nonexposed children was most evident in the first …