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Despite the current availability of diagnostic procedures, the diagnosis of solitary pulmonary nodules still remains challenging. The aim of this clinical study is to evaluate the lung magnetic resonance imaging (MRI) with focused conventional sequences and diffusion weighted imaging.

Methods: we assessed 55 subjects with pulmonary lesions under blinded conditions using a MRI scanner. The exam was carried out with diffusion-weighted sequences (B500 and B1000 DWIBS) and ADC map with a qualitative and quantitative study.

Results: Out of 5 mm nodules (n=23) studied with DWIBS, 16 did not show abnormalities and were unchanged in 1 year follow-up and 3 were not identified compared with CT. DWIBS was positive in 2 cases, false-positive in 1 case and false-negative in 1 case. In 32 lesions >10 mm, histologically confirmed, DWIBS helped the biopsy planning, the definition of neoplastic tissue within …