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Objective —To determine whether dogs with renal failure have higher serum cardiac troponin I (cTnI) concentrations than healthy dogs.

Design —Case-control study.

Animals —31 dogs with renal failure and 51 healthy dogs.

Procedures —Serum concentrations of creatinine and cardiac troponin I, urine specific gravity, and systolic arterial blood pressure were measured for all dogs. Dogs underwent a standardized physical examination, and any dog with evidence of cardiovascular disease or other nonrenal disease was excluded from final analyses. Dogs were considered to be in renal failure when the serum creatinine concentration was ≥ 3.0 mg/dL, urine specific gravity was between 1.007 and 1.030, and renal failure had been clinically diagnosed.

Results —Dogs with renal failure had …