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Antisocial behavior is harmful, financially costly to society, and hard to treat. Callous-unemotional (CU) traits, which predict greater risk for antisocial behavior, are defined in theoretical and diagnostic models as representing low empathy, guilt, and prosociality. However, no meta-analytic reviews have systematically integrated the findings of studies that have reported associations between measures of CU traits and empathy, guilt, or prosociality, or potential moderators of these associations, including gender, age, severity of antisocial behavior, and informant (i.e., self or other reports of measures). To address this gap in the literature, we conducted three separate meta-analyses exploring the association between CU traits and empathy, guilt, and prosociality. In follow-up analyses, we explored associations between CU traits and affective versus cognitive empathy. The results revealed statistically significant and …