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Nonorthogonal multiple access (NOMA) represents a paradigm shift from conventional orthogonal multiple-access (MA) concepts and has been recognized as one of the key enabling technologies for fifth-generation mobile networks. In this paper, the impact of user pairing on the performance of two NOMA systems, i.e., NOMA with fixed power allocation (F-NOMA) and cognitive-radio-inspired NOMA (CR-NOMA), is characterized. For F-NOMA, both analytical and numerical results are provided to demonstrate that F-NOMA can offer a larger sum rate than orthogonal MA, and the performance gain of F-NOMA over conventional MA can be further enlarged by selecting users whose channel conditions are more distinctive. For CR-NOMA, the quality of service (QoS) for users with poorer channel conditions can be guaranteed since the transmit power allocated to other users is constrained following the concept of …