作者
Catherine Williamson, Victoria Geenes
发表日期
2014/7/1
来源
Obstetrics & Gynecology
卷号
124
期号
1
页码范围
120-133
出版商
LWW
简介
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of adverse perinatal outcomes, including spontaneous preterm delivery, meconium staining of the amniotic fluid, and stillbirth. It is commonly treated with ursodeoxycholic acid. There is accumulating evidence to suggest that intrahepatic cholestasis of pregnancy has a lasting influence on both maternal and fetal health. We review the etiology, diagnosis, and management of this intriguing condition.
Intrahepatic cholestasis of pregnancy causes pruritus, deranged liver function, and raised serum bile acids and is associated with an increased risk of adverse perinatal outcomes …
学术搜索中的文章
C Williamson, V Geenes - Obstetrics & Gynecology, 2014