作者
Amarit Tansawet, Pawin Numthavaj, Suphakarn Techapongsatorn, Gareth McKay, John Attia, Oraluck Pattanaprateep, Ammarin Thakkinstian
发表日期
2021/8/1
来源
International Journal of Surgery
卷号
92
页码范围
106053
出版商
LWW
简介
Background
Mesh augmentation has proved efficacious for the prevention of incisional hernia (IH). A recent network meta-analysis (NMA) identified onlay and retrorectus mesh (OM and RM) as the most effective therapeutic options, but the risk of surgical site infection (SSI) and other complications require additional consideration.
Methods
The NMA generated pooled risk differences (RD) for the benefits of reducing IH and the risk of SSI and composite seroma/hematoma (CSH) for use in Monte-Carlo data simulations with 1000 replications. Mean incremental risk-benefit ratios (IRBR), ie, the ratio of incremental risk (or RD) and incremental benefit, and 95% confidence intervals (95% CI) were estimated with a probability of risk-benefits (PRB) across risk-benefit acceptability thresholds from the acceptability curves generated.
Results
The RDs of IH were 0.237 and 0.201 lower in OM and RM than primary suture closure …
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A Tansawet, P Numthavaj, S Techapongsatorn… - International Journal of Surgery, 2021