作者
Seyed Reza Mirhafez, Ahmadreza Zarifian, Mahmoud Ebrahimi, Ramin Fakhre Ale Ali, Amir Avan, Mohammad Tajfard, Mohsen Mohebati, Saeid Eslami, Amir Ali Rahsepar, Hamid Reza Rahimi, Hassan Mehrad-Majd, Gordon A Ferns, Majid Ghayour-Mobarhan
发表日期
2015/6/1
期刊
Clinical biochemistry
卷号
48
期号
9
页码范围
575-580
出版商
Elsevier
简介
Background
We have assessed the association between serum concentrations of 12 cytokines/growth factors and angiographically-defined coronary artery disease, comparing the concentrations in four groups (one control group and three case groups).
Methods
We studied a total of 426 subjects including; 98 control subjects and 3 case groups. The patient groups consisted of: coronary artery bypass graft (CABG) candidates (n = 48) and patients undergoing coronary angiography, with, or without obstructive coronary artery disease. Twelve cytokines (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, MCP-1, IFN-γ, EGF, and VEGF) were measured using a sandwich chemi-luminescence assays, on the Evidence Investigator® system.
Results
The four groups were well matched for demographic and clinical characteristics, except waist circumference, fasting blood glucose (FBG), total and LDL cholesterol and diastolic …
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SR Mirhafez, A Zarifian, M Ebrahimi, RFA Ali, A Avan… - Clinical biochemistry, 2015