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Soybean [Glycine max (L.) Merrill] is an important oilseed crop of the world. Diseases play a major role in yield reduction (Prasad, 2002). Hence, an attempt was made to screen the 204 soybean genotypes against the major diseases both under field and laboratory conditions as one of the management strategies to know their multiple disease resistance nature and the results revealed that only one genotype (EC-241780) against rust and powdery mildew, two genotypes [Birsasoya-1 and JS (SH) 98-22] against anthracnose, powdery mildew and purple seed stain, one genotype [JS (SH) 98-21] against anthracnose, powdery mildew and bud blight, one genotype (Lee) against anthracnose, purple seed stain and bacterial pustule, seven genotypes (DS 98-14, DS-2001, EC-325100, KHSb-2, MACS-708, PS-564 and VLS-64) against powdery mildew, purple seed stain and bud blight, 24 genotypes against powdery …