作者
Alex SF Kwong, José A López-López, Gemma Hammerton, David Manley, Nicholas J Timpson, George Leckie, Rebecca M Pearson
发表日期
2019/6/5
期刊
JAMA Network Open
卷号
2
期号
6
页码范围
e196587-e196587
出版商
American Medical Association
简介
Importance
Less favorable trajectories of depressive mood from adolescence to early adulthood are associated with current and later psychopathology, impaired educational attainment, and social dysfunction, yet the genetic and environmental risk factors associated with these trajectories are not fully established. Examining what risk factors are associated with different trajectories of depressive mood could help identify the nature of depression symptoms and improve preventive interventions for those at most risk.
Objective
To examine the differential associations of genetic and environmental risk factors with trajectories of depression symptoms among individuals observed from ages 10 to 24 years.
Design, Setting, and Participants
In a longitudinal cohort study established in 1990 and currently ongoing (the Avon Longitudinal Study of Parents and Children [ALSPAC]), growth mixture modeling was used to identify …
学术搜索中的文章
ASF Kwong, JA López-López, G Hammerton, D Manley… - JAMA Network Open, 2019