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This paper addresses the following question: why are some university researchers more likely to create spin-off companies than others? In order to explain why university researchers create spin-offs, we draw on the resource-based theory of the firm. The study database consists of 1554 university researchers funded by the Natural Sciences and Engineering Research Council of Canada (NSERC). The logistic regression results suggest that the traditional and entrepreneurial visions of university research complement each other when one looks at the resources mobilized by researchers to launch spin-offs.