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The safety of critical cyber-physical IoT devices hinges on the security of their embedded software that implements control algorithms for monitoring and control of the associated physical processes, e.g., robotics and drones. Reverse engineering of the corresponding embedded controller software binaries enables their security analysis by extracting high-level, domain-specific, and cyber-physical execution semantic information from executables. We present MISMO, a domain-specific reverse engineering framework for embedded binary code in emerging cyber-physical IoT control application domains. The reverse engineering outcomes can be used for firmware vulnerability assessment, memory forensics analysis, targeted memory data attacks, or binary patching for dynamic selective memory protection (e.g., important control algorithm parameters). MISMO performs semantic-matching at an algorithmic level that …