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Based on a review of 40 articles published in the information systems journals of the senior basket since 2006, this article presents refreshing and updated patterns of cross-cultural information systems (CCIS) research and suggests a roadmap for future research in CCIS. This 10-year systematic review contributes to the information systems community by unveiling three streams of transitions in CCIS research: (1) from national level to individual level with espoused and contextual cultural values, (2) from corporate users to end users, and (3) from West to East with the emergence of Chinese culture. The limitations and future research directions are presented.