作者
John E Cannon, Li Su, David G Kiely, Kathleen Page, Mark Toshner, Emilia Swietlik, Carmen Treacy, Anie Ponnaberanam, Robin Condliffe, Karen Sheares, Dolores Taboada, John Dunning, Steven Tsui, Choo Ng, Deepa Gopalan, Nicholas Screaton, Charlie Elliot, Simon Gibbs, Luke Howard, Paul Corris, James Lordan, Martin Johnson, Andrew Peacock, Robert MacKenzie-Ross, Benji Schreiber, Gerry Coghlan, Kostas Dimopoulos, Stephen J Wort, Sean Gaine, Shahin Moledina, David P Jenkins, Joanna Pepke-Zaba
发表日期
2016/5/3
期刊
Circulation
卷号
133
期号
18
页码范围
1761-1771
出版商
Lippincott Williams & Wilkins
简介
Background
Chronic thromboembolic pulmonary hypertension results from incomplete resolution of pulmonary emboli. Pulmonary endarterectomy (PEA) is potentially curative, but residual pulmonary hypertension following surgery is common and its impact on long-term outcome is poorly understood. We wanted to identify factors correlated with poor long-term outcome after surgery and specifically define clinically relevant residual pulmonary hypertension post-PEA.
Methods and Results
Eight hundred eighty consecutive patients (mean age, 57 years) underwent PEA for chronic thromboembolic pulmonary hypertension. Patients routinely underwent detailed reassessment with right heart catheterization and noninvasive testing at 3 to 6 months and annually thereafter with discharge if they were clinically stable at 3 to 5 years and did not require pulmonary vasodilator therapy. Cox regressions were used for survival …
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