作者
Marion Delcroix, Irene Lang, Joanna Pepke-Zaba, Pavel Jansa, Andrea M D’Armini, Repke Snijder, Paul Bresser, Adam Torbicki, Sören Mellemkjaer, Jerzy Lewczuk, Iveta Simkova, Joan A Barberà, Marc de Perrot, Marius M Hoeper, Sean Gaine, Rudolf Speich, Miguel A Gomez-Sanchez, Gabor Kovacs, Xavier Jaïs, David Ambroz, Carmen Treacy, Marco Morsolini, David Jenkins, Jaroslav Lindner, Philippe Dartevelle, Eckhard Mayer, Gérald Simonneau
发表日期
2016/3/1
期刊
Circulation
卷号
133
期号
9
页码范围
859-871
出版商
Lippincott Williams & Wilkins
简介
Background
Chronic thromboembolic pulmonary hypertension, a rare complication of acute pulmonary embolism, is characterized by fibrothrombotic obstructions of large pulmonary arteries combined with small-vessel arteriopathy. It can be cured by pulmonary endarterectomy, and can be clinically improved by medical therapy in inoperable patients. A European registry was set up in 27 centers to evaluate long-term outcome and outcome correlates in 2 distinct populations of operated and not-operated patients who have chronic thromboembolic pulmonary hypertension.
Methods and Results
A total of 679 patients newly diagnosed with chronic thromboembolic pulmonary hypertension were prospectively included over a 24-month period. Estimated survival at 1, 2, and 3 years was 93% (95% confidence interval [CI], 90–95), 91% (95% CI, 87–93), and 89% (95% CI, 86–92) in operated patients (n=404), and only 88 …
学术搜索中的文章
M Delcroix, I Lang, J Pepke-Zaba, P Jansa… - Circulation, 2016