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Industry 5.0 is the digitalization, automation, and data exchange of industrial processes that involve artificial intelligence, industrial Internet of Things (IIoT), and industrial cyber-physical systems (I-CPS). In healthcare, I-CPS enables the intelligent wearable devices to gather data from the real-world and transmit to the virtual world for decision-making. I-CPS makes our lives comfortable with the emergence of innovative healthcare applications. Similar to any other IIoT paradigm, I-CPS capable healthcare applications face numerous challenging issues. The resource-constrained nature of wearable devices and their inability to support complex security mechanisms provide an ideal platform to malevolent entities for launching attacks. To preserve the privacy of wearable devices and their data in an I-CPS environment, in this article we propose a lightweight mutual authentication scheme. Our scheme is based on client …