作者
Niccolò Buetti, Stéphane Ruckly, Etienne de Montmollin, Jean Reignier, Nicolas Terzi, Yves Cohen, Shidasp Siami, Claire Dupuis, Jean-François Timsit
发表日期
2021/2
期刊
Intensive care medicine
卷号
47
页码范围
180-187
出版商
Springer Berlin Heidelberg
简介
Purpose
The primary objective of this study was to investigate the risk of ICU bloodstream infection (BSI) in critically ill COVID-19 patients compared to non-COVID-19 patients. Subsequently, we performed secondary analyses in order to explain the observed results.
Methods
We conducted a matched case-cohort study, based on prospectively collected data from a large ICU cohort in France. Critically ill COVID-19 patients were matched with similar non-COVID-19 patients. ICU-BSI was defined by an infection onset occurring > 48 h after ICU admission. We estimated the effect of COVID-19 on the probability to develop an ICU-BSI using proportional subdistribution hazards models.
Results
We identified 321 COVID-19 patients and 1029 eligible controls in 6 ICUs. Finally, 235 COVID-19 patients were matched with 235 …
学术搜索中的文章
N Buetti, S Ruckly, E de Montmollin, J Reignier, N Terzi… - Intensive care medicine, 2021