作者
Alexander C Razavi, Nathan Wong, Matthew Budoff, Lydia A Bazzano, Tanika N Kelly, Jiang He, Camilo Fernandez, Joao Lima, Joseph F Polak, Morgana Mongraw-Chaffin, Chris deFilippi, Moyses Szklo, Alain G Bertoni, Roger S Blumenthal, Michael J Blaha, Seamus P Whelton
发表日期
2021/1/1
期刊
Cardiovascular Imaging
卷号
14
期号
1
页码范围
219-229
出版商
American College of Cardiology Foundation
简介
Objectives
The purpose of this study was to identify predictors of healthy arterial aging (long-term coronary artery calcification [CAC] of 0) among individuals with metabolic syndrome (MetS) or type 2 diabetes (T2D), which may improve primary prevention strategies.
Background
Individuals with MetS or T2D have a heterogeneously increased risk of atherosclerotic cardiovascular disease and not all have a high-intermediate risk.
Methods
We included 574 participants from the MESA (Multi-Ethnic Study of Atherosclerosis) with MetS or T2D who had CAC=0 at baseline and a repeat CAC scan 10 years later. Multivariable logistic regression assessed the association of traditional and novel atherosclerotic cardiovascular disease risk factors and the MetS severity score (based on the 5 MetS criteria) with healthy arterial aging.
Results
The mean age of participants was 58.9 years, 67% were women, 422 participants …
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AC Razavi, N Wong, M Budoff, LA Bazzano, TN Kelly… - Cardiovascular Imaging, 2021