作者
Ali Hashemi, Eugenie Roudaia, Nicole D Anderson, Claude Alain, Rosanne Aleong, Nasreen Khatri, Morris Freedman, Allison B Sekuler
发表日期
2020/10/20
期刊
Journal of Vision
卷号
20
期号
11
页码范围
1624-1624
出版商
The Association for Research in Vision and Ophthalmology
简介
Alzheimer’s disease (AD) begins years before clinical diagnosis, but there are no simple, cost-effective methods to identify individuals in preclinical stages of AD, when interventions are most likely to succeed. Individuals with AD show deficits in multiple visual functions thought to reflect changes in parieto-occipital and temporal brain regions. However, we know little about how vision changes during preclinical AD–a critical step in determining whether visual tasks can predict AD. Here, we present psychophysical and electrophysiological results for two simplified tasks collected from individuals with mild cognitive impairment (MCI; N= 8; Age= 61-88, MoCA= 20-26) and normal cognition (NC; N= 8; Age= 62-82, MoCA= 23-30). Methods: Face Identification: participants selected which of two briefly presented faces matched a target face identity, measuring accuracy and response time. Contour Integration: we measured …
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