作者
Joëlle Bagautdinova, Josiane Bourque, Valerie J Sydnor, Matthew Cieslak, Aaron F Alexander-Bloch, Maxwell A Bertolero, Philip A Cook, Raquel E Gur, Ruben C Gur, Fengling Hu, Bart Larsen, Tyler M Moore, Hamsanandini Radhakrishnan, David R Roalf, Russel T Shinohara, Tinashe M Tapera, Chenying Zhao, Aristeidis Sotiras, Christos Davatzikos, Theodore D Satterthwaite
发表日期
2023/12/26
期刊
Cell reports
卷号
42
期号
12
出版商
Elsevier
简介
During adolescence, the brain undergoes extensive changes in white matter structure that support cognition. Data-driven approaches applied to cortical surface properties have led the field to understand brain development as a spatially and temporally coordinated mechanism that follows hierarchically organized gradients of change. Although white matter development also appears asynchronous, previous studies have relied largely on anatomical tract-based atlases, precluding a direct assessment of how white matter structure is spatially and temporally coordinated. Harnessing advances in diffusion modeling and machine learning, we identified 14 data-driven patterns of covarying white matter structure in a large sample of youth. Fiber covariance networks aligned with known major tracts, while also capturing distinct patterns of spatial covariance across distributed white matter locations. Most networks showed …
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