作者
Raphael Bueno, William G Richards, Scott J Swanson, Michael T Jaklitsch, Jeanne M Lukanich, Steven J Mentzer, David J Sugarbaker
发表日期
2000/12/1
期刊
The Annals of thoracic surgery
卷号
70
期号
6
页码范围
1826-1831
出版商
Elsevier
简介
Background
This study was undertaken to determine the predictive value of nodal status at resection in regards to long-term outcome of patients undergoing neo-adjuvant therapy and resection for stage IIIA N2-positive non-small cell lung cancer (NSCLC).
Methods
We reviewed the medical records of all patients found on surgical staging to have N2-positive NSCLC and who underwent induction therapy followed by resection between 1988 and 1996 at our hospital. Complete follow-up information was examined utilizing Kaplan-Meier survival analysis and Cox proportional hazards multivariate analysis.
Results
One hundred three patients (59 men) with stage IIIA N2-positive NSCLC received neoadjuvant therapy before surgical resection. Preoperative therapy consisted of platinum-based chemotherapy (76), radiotherapy (18), or chemoradiation (9). Operations included pneumonectomy (38), bilobectomy (6), and …
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R Bueno, WG Richards, SJ Swanson, MT Jaklitsch… - The Annals of thoracic surgery, 2000