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Extended producer responsibility (EPR), in which the producers are made responsible for the end-of-life disposal of EEE, is a widely used approach to manage e-waste, both in developed as well as developing countries. Within the EPR framework, a range of policy instruments such as mandatory take back, recycling rate targets, and deposit-refund systems are adopted by various countries to ensure environmentally safe disposal of e-waste. India’s E-waste (Management and Handling) Rules, 2011, which came into effect in May 2012, use EPR framework for e-waste management, which is currently dominated by informal markets. In an amendment to these regulations in October 2016, the Indian government has introduced new policy instrument in which the producers have to meet certain e-waste collection targets and implement a deposit-refund system. In this paper, we extensively review the theoretical literature on policy instruments within the EPR framework to first show that the simple mandatory take back provision does not provide incentives to either the producers or the consumers and then analyse the incentive effects of alternative policy instruments compatible with EPR framework. We then draw on the empirical literature on implementation of various policy instruments in developing countries to draw implications for EPR policy design and implementation in India.