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The synergy between computational clouds and non-HPC scientific applications (sometimes referred to as “midrange computing”) is highlighted in recent institutional reports concerning, such as the Magellan Report on Cloud Computing for Science [1] and the CERN Strategic Plan for a Scientific Cloud Computing Infrastructure for Europe [2]. From a scientific standpoint, the goal of the presented work is therefore to address issues which hamper the exploitation of clouds in support of medical research within the VPH community. The objectives include detailed analysis of medical application requirements with regard to data security and curation, designing a suitable platform, enabling application services to be shared in a controlled way and performing assessment of the system.