作者
S Farrokhi, M Hojjat‐Farsangi, MK Noohpisheh, R Tahmasbi, N Rezaei
发表日期
2005/11
期刊
Journal of the European Academy of Dermatology and Venereology
卷号
19
期号
6
页码范围
706-711
出版商
Blackwell Science Ltd
简介
Background Vitiligo is an acquired idiopathic hypomelanotic disorder characterized by circumscribed depigmented macules resulting from the loss of cutaneous melanocytes.
Objective In order to evaluate the immune system of Iranian patients with vitiligo, this study was accomplished.
Methods Fifty‐five Iranian patients with vitiligo and 60 healthy persons as control were investigated in this study. The laboratory techniques were included: antimelanocyte antibody (AMA) and antinuclear antibody (ANA) with indirect immunoflorescent test, C3 and C4 levels with single radial immunodiffusion (SRID), and rheumatoid factor (RF) with enzyme‐linked immunosorbent assay (ELISA).
Results AMA was positive in 17 patients (30.9%) and was negative in the entire control group (P < 0.0001). ANA was positive in 4 patients (7.3%), which was insignificantly higher than control group (1.7%). IgM‐RF was positive in 6 …
学术搜索中的文章
S Farrokhi, M Hojjat‐Farsangi, MK Noohpisheh… - Journal of the European Academy of Dermatology and …, 2005