作者
Amanda Leach, Patrick A Twumasi, Samuel Kumah, Winston S Banya, Shabbar Jaffar, Bruce D Forrest, Dan M Granoff, Daniel E LiButti, George M Carlone, Lorna B Pais, Claire V Broome, Brian M Greenwood
发表日期
1997/1/1
期刊
Journal of Infectious Diseases
卷号
175
期号
1
页码范围
200-204
出版商
The University of Chicago Press
简介
Two hundred twenty-one Gambian children vaccinated previously with one, two, or three doses of a meningococcal conjugate vaccine or two doses of polysaccharide vaccine before the age of 6 months were revaccinated at the age of 18-24 months with either meningococcal polysaccharide, conjugate, or inactivated polio vaccines. Children who had previously received one, two, or three doses of conjugate vaccine had significantly (P < .001) higher anti-group C meningococcal antibody levels following revaccination than did children vaccinated with a polysaccharide vaccine for the first time. Children vaccinated previously with two doses of polysaccharide vaccine had a lower group C antibody response than did control children. Group A antibody responses following revaccination of children who had previously received polysaccharide or conjugate vaccine were not significantly higher than those in control …
引用总数
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