作者
Pauline McLoone, Aizhan Zhumbayeva, Sofiya Yunussova, Yerkhat Kaliyev, Ludmila Yevstafeva, Susan Verrall, Julie Sungurtas, Ceri Austin, J Will Allwood, Gordon J McDougall
发表日期
2021/12
期刊
BMC Complementary Medicine and Therapies
卷号
21
页码范围
1-11
出版商
BioMed Central
简介
Background
Antimicrobial drug resistance is a major public health threat that can render infections including wound and skin infections untreatable. The discovery of new antimicrobials is critical. Approaches to discover novel antimicrobial therapies have included investigating the antimicrobial activity of natural sources such as honey. In this study, the anti-microbial activity and chemical composition of 12 honeys from Kazakhstan and medical grade manuka honey were investigated.
Methods
Agar well diffusion and broth culture assays were used to determine anti-microbial activity against a range of skin and wound infecting micro-organisms. Folin-Ciocalteu method was used to determine the total phenol content of the honeys and non-targeted liquid chromatography analysis was performed to identify components that correlated with antimicrobial activity …
学术搜索中的文章
P McLoone, A Zhumbayeva, S Yunussova, Y Kaliyev… - BMC Complementary Medicine and Therapies, 2021