作者
Jolanda Sabatino, Salvatore De Rosa, Isabella Leo, Antonio Strangio, Sabrina La Bella, Sabato Sorrentino, Annalisa Mongiardo, Carmen Spaccarotella, Alberto Polimeni, Ciro Indolfi
发表日期
2021/7/1
期刊
Open Heart
卷号
8
期号
2
页码范围
e001685
出版商
Archives of Disease in childhood
简介
Aims
To investigate the changes in left atrial strain (LAS) after correction of severe aortic stenosis (AS) with transcatheter aortic valve replacement (TAVR) and assess its prognostic impact.
Methods and results
One hundred consecutive patients with severe symptomatic AS who underwent TAVR at the Magna Graecia University of Catanzaro underwent echocardiographic examination including assessment of LAS before and after TAVR. Independent investigators collected outcome data and information. The primary study outcome was the difference in ΔLAS (postTAVR–preTAVR) between patients those met the main clinical endpoint (a composite of cardiovascular mortality and heart failure hospitalisation) and those not meeting the endpoint.
During a median follow-up of 31 months, 35 patients (35%) met the combined clinical endpoint. The difference between LAS post-TAVR and LAS pre-TAVR (ΔLAS) was …
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