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For the first time, a novel flat-gain optical amplifier is proposed using a hybrid configuration with an Er-Yb co-doped waveguide amplifier (EYDWA) and a semiconductor optical amplifier (SOA) for 100 × 10-Gb/s dense wavelength division multiplexed system at 0.2 nm interval. With an EYDWA-SOA hybrid amplifier, a flat gain of is obtained across the effective bandwidth with a gain variation of the order of 0.75 dB without using any gain clamping techniques. It is observed that when the proposed hybrid amplifier is used as a booster for hybrid distributed Raman amplifier and erbium doped fiber amplifier, the gain variation is reduced from 2.01 to ~ 1.15 dB efficiently with acceptable bit error rate.