作者
Jianwen Wang, Dirar S Khoury, Yong Yue, Guillermo Torre-Amione, Sherif F Nagueh
发表日期
2008/5/1
期刊
European heart journal
卷号
29
期号
10
页码范围
1283-1289
出版商
Oxford University Press
简介
Aims
To examine myocardial deformation and rotation in patients with heart failure, and elucidate the underlying mechanisms that account for normal ejection fraction (EF) in patients with diastolic heart failure (DHF).
Methods and results
Fifty consecutive patients presenting with congestive heart failure (age: 58 ± 16 years) underwent simultaneous right heart catheterization and transthoracic echocardiography. Left ventricular (LV) volumes, mass, EF, meridional, and circumferential wall stress were measured in addition to haemodynamic measurements. 2-D speckle tracking was applied to measure longitudinal, radial, and circumferential strain and twist. Twist was reduced only in patients with systolic heart failure (SHF: 5 ± 2°, DHF: 13 ± 6°, control: 14 ± 5°, P < 0.001). Circumferential strain was not different between DHF (−15 ± 5%) and control groups (−20 ± 3%, P > 0.05 …
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