作者
Chris Cameron, Doug Coyle, Trevor Richter, Shannon Kelly, Kasandra Gauthier, Sabine Steiner, Marc Carrier, Kathryn Coyle, Annie Bai, Kristen Moulton, Tammy Clifford, George Wells
发表日期
2014
期刊
BMJ Open
期号
4
简介
Objective
To examine the comparative efficacy and safety of antithrombotic treatments (apixaban, dabigatran, edoxaban, rivaroxaban and vitamin K antagonists (VKA) at a standard adjusted dose (target international normalised ratio 2.0–3.0), acetylsalicylic acid (ASA), ASA and clopidogrel) for non-valvular atrial fibrillation and among subpopulations.
Design
Systematic review and network meta-analysis.
Data sources
A systematic literature search strategy was designed and carried out using MEDLINE, EMBASE, the Cochrane Register of Controlled Trials and the grey literature including the websites of regulatory agencies and health technology assessment organisations for trials published in English from 1988 to January 2014.
Eligibility criteria for selecting studies
Randomised controlled trials were selected for inclusion if they were published in English, included at least one antithrombotic treatment and …
引用总数
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