作者
Jason D Merker, Geoffrey R Oxnard, Carolyn Compton, Maximilian Diehn, Patricia Hurley, Alexander J Lazar, Neal Lindeman, Christina M Lockwood, Alex J Rai, Richard L Schilsky, Apostolia M Tsimberidou, Patricia Vasalos, Brooke L Billman, Thomas K Oliver, Suanna S Bruinooge, Daniel F Hayes, Nicholas C Turner
发表日期
2018/10/1
来源
Archives of pathology & laboratory medicine
卷号
142
期号
10
页码范围
1242-1253
出版商
the College of American Pathologists
简介
Purpose
Clinical use of analytical tests to assess genomic variants in circulating tumor DNA (ctDNA) is increasing. This joint review from the American Society of Clinical Oncology and the College of American Pathologists summarizes current information about clinical ctDNA assays and provides a framework for future research.
Methods
An Expert Panel conducted a literature review on the use of ctDNA assays for solid tumors, including preanalytical variables, analytical validity, interpretation and reporting, and clinical validity and utility.
Results
The literature search identified 1338 references. Of those, 390, plus 31 references supplied by the Expert Panel, were selected for full-text review. There were 77 articles selected for inclusion.
Conclusions
The evidence indicates that testing for ctDNA is optimally performed on plasma collected in cell …
学术搜索中的文章
JD Merker, GR Oxnard, C Compton, M Diehn, P Hurley… - Archives of pathology & laboratory medicine, 2018