作者
Patrick B Mark, Juan J Carrero, Kunihiro Matsushita, Yingying Sang, Shoshana H Ballew, Morgan E Grams, Josef Coresh, Aditya Surapaneni, Nigel J Brunskill, John Chalmers, Lili Chan, Alex R Chang, Rajkumar Chinnadurai, Gabriel Chodick, Massimo Cirillo, Dick De Zeeuw, Marie Evans, Amit X Garg, Orlando M Gutierrez, Hiddo JL Heerspink, Gunnar H Heine, William G Herrington, Junichi Ishigami, Florian Kronenberg, Jun Young Lee, Adeera Levin, Rupert W Major, Angharad Marks, Girish N Nadkarni, David MJ Naimark, Christoph Nowak, Mahboob Rahman, Charumathi Sabanayagam, Mark Sarnak, Simon Sawhney, Markus P Schneider, Varda Shalev, Jung-Im Shin, Moneeza K Siddiqui, Nikita Stempniewicz, Keiichi Sumida, José M Valdivielso, Jan Van Den Brand, Angela Yee-Moon Wang, David C Wheeler, Lihua Zhang, Frank LJ Visseren, Benedicte Stengel
发表日期
2023/4/1
期刊
European heart journal
卷号
44
期号
13
页码范围
1157-1166
出版商
Oxford University Press
简介
Aims
Chronic kidney disease (CKD) increases risk of cardiovascular disease (CVD). Less is known about how CVD associates with future risk of kidney failure with replacement therapy (KFRT).
Methods and results
The study included 25 903 761 individuals from the CKD Prognosis Consortium with known baseline estimated glomerular filtration rate (eGFR) and evaluated the impact of prevalent and incident coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) events as time-varying exposures on KFRT outcomes. Mean age was 53 (standard deviation 17) years and mean eGFR was 89 mL/min/1.73 m2, 15% had diabetes and 8.4% had urinary albumin-to-creatinine ratio (ACR) available (median 13 mg/g); 9.5% had prevalent CHD, 3.2% prior stroke, 3.3% HF, and 4.4% prior AF. During follow-up, there were 269 142 CHD, 311 021 stroke, 712 556 …
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PB Mark, JJ Carrero, K Matsushita, Y Sang, SH Ballew… - European heart journal, 2023